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The combination therapy comprising Quercetin, Gallic Acid, Coenzyme Q10, Nano Curcumin, Bioflavonoids, Ginger Extract, L-Arginine, Vitamin C, Iron, Potassium, Calcium, Phosphorus, Copper, Tin, Nickel, Selenium, Chloride, Manganese, Silicon, Boron, and Vanadium is designed to synergistically enhance antioxidant defenses, support cardiovascular health, modulate inflammation, and provide essential micronutrients. Below is a detailed analysis of each component, including their roles, recommended dosages, indications, contraindications, and references to scientific literature

Price: Rs. 499.00 Product Dimension: 10*10

1. The proposed combination therapy includes a variety of bioactive compounds and minerals, each selected for their potential health benefits. Below is a detailed analysis of each ingredient, including their roles, recommended dosages, indications, contraindications, and relevant scientific references.

1. Quercetin (100 mg)

  • Role: Quercetin is a flavonoid with potent antioxidant and anti-inflammatory properties. It helps scavenge free radicals and modulate inflammatory pathways.
  • Recommended Dosage: Supplementation typically ranges from 500 mg to 1,000 mg daily, divided into two doses. The provided dosage of 100 mg is below the commonly studied range.
  • Indications: Allergic conditions, cardiovascular diseases, and chronic inflammatory states.
  • Contraindications: Potential interactions with antibiotics (e.g., fluoroquinolones) and anticoagulants. Individuals with kidney disease should exercise caution.
  • References:

2. Gallic Acid (15 mcg)

  • Role: Gallic acid is a phenolic compound with antioxidant, anti-inflammatory, and antimicrobial properties.
  • Recommended Dosage: No established dosage for supplementation; typically obtained through dietary sources. The provided dosage of 15 mcg is minimal.
  • Indications: Antioxidant support and potential anticancer properties.
  • Contraindications: No well-documented contraindications; generally considered safe through dietary intake.

3. Coenzyme Q10 (150 mg)

4. Nano Curcumin (200 mg)

  • Role: Curcumin, the active component of turmeric, exhibits anti-inflammatory, antioxidant, and anticancer properties. Nano-formulation enhances its bioavailability.
  • Recommended Dosage: Standard curcumin doses range from 500 mg to 2,000 mg daily. Nano-formulations may require lower dosages due to increased absorption. The provided dosage of 200 mg is within a reasonable range for nano-formulations.
  • Indications: Inflammatory diseases, arthritis, and metabolic syndrome.
  • Contraindications: Gallbladder disease and risk of bleeding.

5. Bioflavonoids (10 mg)

  • Role: Bioflavonoids are plant compounds with antioxidant and anti-inflammatory effects, supporting vascular health and enhancing vitamin C absorption.
  • Recommended Dosage: No established dosage; typically consumed through a diet rich in fruits and vegetables.
  • Indications: Capillary fragility and support of cardiovascular health.
  • Contraindications: Generally considered safe; excessive intake may interfere with certain medications.

6. Ginger Extract (67 mg and 50 mg)

  • Role: Ginger possesses anti-inflammatory, antioxidant, and antiemetic properties.
  • Recommended Dosage: Doses of 250 mg to 1,000 mg daily are common. The combined dosage of 117 mg is below typical therapeutic ranges.
  • Indications: Nausea, osteoarthritis, and digestive support.
  • Contraindications: Bleeding disorders and gallstones.

7. L-Arginine (60 mg)

  • Role: L-Arginine is a precursor to nitric oxide, facilitating vasodilation and supporting cardiovascular health.
  • Recommended Dosage: Commonly 2 g to 6 g daily. The provided dosage of 60 mg is significantly below therapeutic levels.
  • Indications: Hypertension, angina, and erectile dysfunction.
  • Contraindications: Herpes infections and recent myocardial infarction.

8. Vitamin C (Ascorbic Acid) (100 mg)

  • Role: Vitamin C is an essential nutrient with antioxidant properties, supporting immune function and collagen synthesis.
  • Recommended Dosage: The recommended daily allowance (RDA) is 75 mg for women and 90 mg for men. The provided dosage of 100 mg meets daily requirements.
  • Indications: Scurvy prevention, immune support, and antioxidant protection.
  • Contraindications: High doses may cause gastrointestinal disturbances.

9. Iron (17 mg)

  • Role: Iron is vital for hemoglobin formation and oxygen transport.
  • Recommended Dosage: The RDA is 8 

Here is a brief overview of the next listed ingredients, including their roles, recommended dosages, indications, contraindications, and references:

10. Potassium (10 mg)

  • Role: Essential for maintaining electrolyte balance, muscle contraction, and nerve function.
  • Recommended Dosage: The RDA for adults is 2,500–3,400 mg/day. The provided 10 mg is minimal.
  • Indications: Hypertension, muscle cramps, and cardiovascular health.
  • Contraindications: Kidney disease and hyperkalemia risk.

11. Calcium (5 mg)

  • Role: Crucial for bone health, nerve signaling, and muscle function.
  • Recommended Dosage: The RDA is 1,000–1,200 mg/day. The provided 5 mg is very low.
  • Indications: Osteoporosis prevention, bone health support.
  • Contraindications: Hypercalcemia, kidney stones.

12. Phosphorus (3.86 mg)

  • Role: Supports bone health, energy production, and cell repair.
  • Recommended Dosage: The RDA is 700 mg/day. The provided 3.86 mg is negligible.
  • Indications: Bone metabolism, ATP production.
  • Contraindications: Chronic kidney disease, hyperphosphatemia.

13. Copper (1.7 mg)

  • Role: Essential for iron metabolism, immune function, and collagen production.
  • Recommended Dosage: The RDA is 0.9 mg/day. The provided 1.7 mg is slightly above the requirement.
  • Indications: Anemia, connective tissue disorders.
  • Contraindications: Wilson’s disease, copper toxicity.

14. Tin (130 mcg)

  • Role: Trace element with uncertain biological function in humans.
  • Recommended Dosage: No established RDA.
  • Indications: Potential enzyme cofactor (uncertain).
  • Contraindications: High doses may be toxic.

15. Nickel (35 mcg)

  • Role: Trace mineral involved in enzymatic reactions.
  • Recommended Dosage: Estimated safe intake is 25–100 mcg/day.
  • Indications: Potential role in iron metabolism.
  • Contraindications: Nickel allergy, toxicity in excess.

16. Selenium (2 mcg)

  • Role: Antioxidant, supports thyroid function and immune health.
  • Recommended Dosage: The RDA is 55 mcg/day. The provided 2 mcg is very low.
  • Indications: Thyroid disorders, immune health.
  • Contraindications: Selenium toxicity, selenosis.

17. Chloride (9.7 mcg)

  • Role: Essential for fluid balance, digestion (HCl in the stomach).
  • Recommended Dosage: The RDA is 2,300 mg/day. The provided 9.7 mcg is extremely low.
  • Indications: Electrolyte balance.
  • Contraindications: Hyperchloremia (often due to dehydration).

18. Manganese (4 mg)

  • Role: Supports bone development, antioxidant function, and enzyme activation.
  • Recommended Dosage: The AI (adequate intake) is 1.8–2.3 mg/day. The provided 4 mg is slightly above the RDA.
  • Indications: Osteoarthritis, metabolic health.
  • Contraindications: Neurotoxicity at high doses.

19. Silicon (2 mg)

  • Role: Supports collagen formation and bone health.
  • Recommended Dosage: No official RDA, but 10–25 mg/day is suggested for benefits. The provided 2 mg is minimal.
  • Indications: Bone strength, hair and nail health.
  • Contraindications: No major known issues.

20. Boron (1 mg)

  • Role: Supports bone health, cognitive function, and hormonal regulation.
  • Recommended Dosage: Suggested intake is 1–3 mg/day. The provided 1 mg aligns with this.
  • Indications: Bone metabolism, inflammation reduction.
  • Contraindications: High doses may affect hormones.

21. Vanadium (10 mcg)

  • Role: May support insulin sensitivity and blood sugar regulation.
  • Recommended Dosage: No official RDA, but intakes of 10–30 mcg/day are suggested.
  • Indications: Potential diabetes management aid.
  • Contraindications: High doses may cause toxicity.